Reduced Side Effects for all, Increased Potential for Prolonged Survival in Some
Primary brain tumors are difficult to treat, depending upon the proximity of the tumor to the many essential organs in the region. By reducing radiation dose to these organs, proton therapy can decrease side effects and risks, and/or allow higher doses of radiation to increase the chance of prolonged survival.
Current indications for proton therapy for adult primary Brain tumors, and the benefits of proton treatment, include:
Low- grade glioma (Diffuse astrocytoma, oligodendroglioma, etc.)
- Patients exhibit stability in cognitive function 
- QOL assessment revealed no change over time 
High- grade glioma (Anaplastic astrocytoma, anaplastic oligodendroglioma, glioblastoma, etc.)
- Proton therapy improves patient tolerance of high-dose radiation therapy necessary to prolong overall survival
Meningioma (benign, atypical, malignant, etc.)
- Proton therapy roughly decreases the total radiation dose delivered to the brain by half dramatically diminishing the risk of late radiation induced cancers 
Recurrent brain tumors following conventional radiation therapy
- Proton therapy allows for effective radiation dose delivery while sparing normal tissues that have previously been irradiated 
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